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HOTTOPS Diabetes Fall 2016

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T he American Diabetes Association's 76 t h Scientific Session took place June 10 to 14, 2016, in New Orleans, Louisiana. In a presentation titled "Is there a racial difference in the mean continuous glucose monitoring glucose in relation to the A1C?" Rose Gubitosi-Klug, MD, PhD, discussed findings from a multi-center observational study that sought to determine whether a racial difference exists in the association of mean glucose with HbA1c between non-Hispanic African Americans and non-Hispanic Whites with type 1 diabetes (T1D), and in particular to determine whether HbA1c levels overestimate mean glucose in non-Hispanic African Americans compared with non-Hispanic Whites. A total of 208 participants were recruited (104 non-Hispanic African American and 104 non- Hispanic white) and had a blinded continuous glucose monitoring (CGM) sensor inserted and worn during the study period. Main outcomes included change in HbA1c, fructosamine, glycated albumin, hemoglobin electrophoresis, total CBC with indices, reticulocyte counts, serum creatinine, and total bilirubin from enrollment to participants' final visit. The results of their study were consistent with the hypothesis—data showed a 0.8% increase in mean A1c between African Americans and Whites that reflected only a 10 mg/dl difference in mean glucose. 143-LB: Sociodemographic Factors Predict Hospitalizations for Uncontrolled Hyperglycemia and Hypoglycemic Complications among Diabetics in the US The authors conducted a study to to examine the impact of socioeconomic factors on hospitalizations for uncontrolled hyperglycemia (HY) and hypoglycemia (HO) among individuals with diabetes in the US. Utilizing the Nationwide Inpatient Sample (NIS) from the years 2009–2011, they identified all adult hospitalizations among patients with type 1/type 2 diabetes mellitus (DM) in the US. Difference in primary outcome by gender, race (white, black, Hispanic, other), income quartile and primary payer were studied. The authors concluded that males, blacks, lower income quartiles and having non Medicare/non private insurance (i.e. Medicaid or other insurance) are independently associated with a higher rate in hospitalizations for acute HY/HO complications Fall 2016 Conference Highlights The Role of Continuous Glucose Monitoring in Diabetes Management American Diabetes Association's 76 t h Scientific Session June 2016 • New Orleans, Louisiana D i a b e t e s , O b e s i t y, a n d C a r d i o v a s c u l a r D i s e a s e M a n a g e m e n t HOT Peer-reviewed, evidence-based content for physicians T O P I C S in To download a PDF of the study protocol, click HERE To view presentations from the ADA 2016 session Race/Ethnic Differences Matter, click HERE Read the full abstract HERE Read the full abstract HERE 85-LB: Time Effects of the Exercise Test on Glucose Variability among Patients with Type 1 Diabetes Researchers aimed to examine the hourly glucose variability after the exercise stress test with real-time data. Data were collected from 15 young adults with type 1 diabetes aged 19 to 33 years (6 males and 9 females). They found that hourly standard deviation of glucose changed most significantly among study participants 6 hours after the stress test and the widest variation was shown 12 hours after the test. They concluded that the dose would potentially need to be adjusted for an extended period of time after the stress test since insulin hypersensitivity can be a marker for hypoglycemia. To view more studies in the T1D Exchange, click HERE SELECTED ABSTRACTS Supported by

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